Teaching MCC CUREs

CUREs are a highly effective way to support student achievement and persistence and allow every student in a program to experience firsthand the scientific process as an integral part of their education. In addition, CUREs are cost-effective ($$ and faculty time) and don’t require students to commit to time outside their usual academic schedule (often a barrier to under-represented students). For more detailed information on CUREs and for MDH-related pedagogical research, visit the OUR CUREs Community and other links shared below.

• Key Elements of a CURE

  Research Elements of an MDH CURE

  OUR Community Key Component Expanded Description

  CURES to teach Biological Thinking (Bell BAMBED 2020)

  Example Hypothesis Development for MDH-CS Interaction CURE

• Example MDH CURE Syllabi

  Full Semester Template

  Modular Example Template

  Community College

  N. Hennepin CC -Biology Focus

  SW CC -Chemistry Focus

  Primarily Undergraduate Institution

  Upper Div Biochem Lab 1

  Upper Div Biochem Lab 2

  Upper Div Biochem Lab 3

  Comprehensive and R1 University

  Upper Div Biochem Lab 1

  Upper Div Biochem Lab 2

  Upper Div Biochem Lab 3

  First Year Chem & Biol

  First Year Chem - Full Semester Drug Design

  First Year Chem -Modular MDH & Cancer

  Hybrid and Virtual

  Virtual CURE

  Have a syllabi or link to your MDH CURE you want to share? Email your hub leader (Ellis Bell, Lisa Gentile Amy Springer) or Joseph Provost.

• Learning Goals and Assessments

  Hypothesis Development Rubrics

  - Find and present relevant primary literature and supporting evidence for hypothesis development

  - Understand the roles that non-covalent interactions play in enzyme structure and function

  - Develop and present a testable hypothesis with appropriate experiments

  OUR Pedagogical Key Components, Goals and Assessment

• MDH CURE Publications

  Publications (papers and reviews)

  CUREs in biochemistry-where we are and where we should go

  Development and Use of CUREs in Biochemistry

  Using Bioinformatics and Molecular Visualization to Develop Student Hypotheses in a Malate Dehydrogenase Oriented CURE

  External Collaboration Results in Student Learning Gains and Positive STEM Attitudes in CUREs

  Length of course-based undergraduate research experiences (CURE) impacts student learning and attitudinal outcomes: A study of the Malate dehydrogenase CUREs Community (MCC)

  Increasing access for biochemistry research in undergraduate education: The malate dehydrogenase CURE community

  Developing Course Undergraduate Research Experiences (CUREs) in Chemistry

  Using inquiry and research-based learning in a year-long biochemistry laboratory: Part I-guided inquiry-purification and characterization of a fusion protein: Histidine tag, malate dehydrogenase, and green fluorescent protein

  Using inquiry and research-based learning in a year-long biochemistry laboratory : Part II-research-based laboratory-a semester-long research approach using malate dehydrogenase as a research model

  It is all about the students…

  Project: Malate Dehydrogenase CURE Community

  Abstracts

  The Evolution of the Malate Dehydrogenase CUREs Community

  Community college course-based undergraduate research experiences in chemistry, biochemistry and biology classes resulted in significant student gains for persons excluded due to ethnicity or race

  Creating and Using the Malate Dehydrogenase CURE Community to Explore Critical Aspects of Sustainable Protein Centric CUREs

  Protein Engineering of a Spectroscopic Probe into Malate Dehydrogenase (MDH)

  MDH CURE Community Faculty Fellows: A new mentoring program supporting Biochemistry CUREs

  Authentic research in the teaching laboratory at a large university: comparative studies of malate dehydrogenase isoforms in trypanosomes

  MDH protein interactions and phosphorylation: Engaging students with a novel scientific theme using CUREs

  OTHER

  AddGene Course-Based Undergraduate Research Experiences (CUREs)

  Send J Provost links to your publications, abstracts or other materials to include on this page.

• New to Teaching MDH CURES?

  Start Up Page

  Suggested Equipment List

  Teamwork and Colalboration

  Key Elements of MDH CUREs

  Tips and Hints to Teaching a CURE

  MCC Discount at BioRad (Save up to 60% off Bio-Rad list prices! MCC is a Bio-Rad Explorer education program preferred pricing partner and members can receive additional discounts on equipment, reagents, and consumables for their MCC courses – Go to the Members Only Page to find links to save!)

• Cohort 2023 Workshop

  Information here will be used at the 2023 MCC Fellows Cohort workshop in Boston.

  • Agenda/Itinerary

  • 1 ml Enzyme Assay

  • Purification PPT

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CURE Pedagogical Research …

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OUR CURES

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CUREnet

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BASIL

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CRISPR CURES

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