Videos

This page is a collection of all videos posted throughout the MCC website

Introduction to MDH CUREs Community (NSF Showcase)

Background on MDH CURE Research Projects

MDH CURES: Human MDH PPI & PTM Review

MDH CURES: Allostery, Loop, Structure…

MDH CURES: MDH CS Metabolon

MDH CURES:Alt Approach to MDH-HIS Purification

MDH CURES: PTM Phosphorylation

MDH CURES: PTM Ribosylation

Protocols, Assays and Techniques

MDH Assay Tricks, Tips and Hacks

Recombinant Purification PT 1 Plasmids, Strains and Transformation

Recombinant Purification Pt 2 Culture Lysis and Induction

Recombinant Purification Pt 3 Protein Purification

Graphing Kinetics Data on Excel: A tutorial

TBA

How to use SnapGene to design SDM Primers for NEBQ5

TBA

Virtual Workshops

2023 Protein Society CUREs Presentation

2023 MCC Workshop Day 2 - Techniques

Key Elements of an MDH CURE 2026

Designing your MDH CURE Syllabus 2026

2023 Creating your First MDH CURE

Intro and helpful hints of Hypothesis Design

MDH CURES for Intro Courses

Designing your Syllabus Podcast 2026

MDH_CURE_Syllabus_podcast.m4a

Gen Chem Drug Design Cohort ‘26 Theme

C-Tail PTM Cohort ‘26 Theme

MDH CURE Syllabus Intro 2026

MDH Computational Methods 2026

Bioinformatics and Computational MCC Videos

Part I: Introduction to teaching an undergraduate biochemistry laboratory as a CURE

Part II: Preparing a Protein Structure and Computational Approaches

Part III: Structure Refinement - RefineD

Part IV: Structure Validation - MolProbity

Part V: Creating Multimeric Proteins – HawkDock, PyMol

Part VI: Probing Protein Conformation & Local Environment – H++

Part VIII: Mapping Surface Properties using Fragment Mapping with SwissDock

Part IX: Exploring Protein Interactions with Other Proteins or Small Molecules

Part X: Examples of Binding Studies with Malate Dehydrogenase

MDH Journal Club & MDH Science Workshops

Introduction to MDH Structure and Function

Journal Club: MDH Mechanism of Catalysis

Journal Club: Kinetic Mechanism

NMR Applications for MDH CURE

MDH Science: MDH Phosphorylation

MDH Science: Tools to Study MDH

MDH Science: Review of Structure, Allostery and Kinetics

MDH/MCC Publication Videos

BCA Assay for Assaying MDH (link to paper)

An alternative method to measure MDH activity using a spec in the vis wavelength range

Coming Soon

The Role of the Flexible Loop (Paper Link)

Coming soon