Videos

This page is a collection of all videos posted throughout the MCC website

Introduction to MDH CUREs Community (NSF Showcase)

Background on MDH CURE Research Projects

MDH CURES: Human MDH PPI & PTM Review

MDH CURES: Allostery, Loop, Structure…

MDH CURES: MDH CS Metabolon

MDH CURES:Alt Approach to MDH-HIS Purification

MDH CURES: PTM Phosphorylation

MDH CURES: PTM Ribosylation

Protocols, Assays and Techniques

MDH Assay Tricks, Tips and Hacks

Recombinant Purification PT 1 Plasmids, Strains and Transformation

Recombinant Purification Pt 2 Culture Lysis and Induction

Recombinant Purification Pt 3 Protein Purification

Graphing Kinetics Data on Excel: A tutorial

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Virtual Workshops

2023 Protein Society CUREs Presentation

2023 MCC Workshop Day 2 - Techniques

2023 MCC Virtual Cohort Meeting - Creating your First MDH CURE

Tips and help for creating your MDHRE

Intro and helpful hints of Hypothesis Design

Bioinformatics and Computational MCC Videos

Part I: Introduction to teaching an undergraduate biochemistry laboratory as a CURE

Part II: Preparing a Protein Structure and Computational Approaches

Part III: Structure Refinement - RefineD

Part IV: Structure Validation - MolProbity

Part V: Creating Multimeric Proteins – HawkDock, PyMol

Part VI: Probing Protein Conformation & Local Environment – H++

Part VIII: Mapping Surface Properties using Fragment Mapping with SwissDock

Part IX: Exploring Protein Interactions with Other Proteins or Small Molecules

Part X: Examples of Binding Studies with Malate Dehydrogenase

MDH Journal Club & MDH Science Workshops

Journal Club: MDH Mechanism of Catalysis

Journal Club: Kinetic Mechanism

MDH Science: MDH Phosphorylation

MDH Science: Tools to Study MDH

Using Primary Literature in Your CURE

Metabolons

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Active Site Loop & Substrate Specificity

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Cofactor Specificity

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Subunit Interface & Allosteric Interactions

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